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June 9, 2022
Original Investigation

Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1818

This randomized clinical trial evaluates the impact of daily ω-3 supplementation on the development of incident dry eye disease.

Brief Report

Early-Onset TIMP3-Related Retinopathy Associated With Impaired Signal Peptide

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1822

This case series evaluates the phenotype and underlying biochemical mechanism of disease-causing TIMP3 variants altering the N-terminal signal peptide in 2 families.

Invited Commentary

Another Disappointment for ω-3 Fatty Acid and Dry Eye Disease

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1821
JAMA Ophthalmology Clinical Challenge

Sudden-Onset Monocular Blurry Vision in a Young Woman

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1327

A 32-year-old woman with fever, flulike symptoms, and altered mental status developed sudden-onset blurry vision in her right eye. Following intravenous antibiotics and antivirals, laboratory and imaging results were negative and her mental status improved but blurry vision persisted in the right eye. What would you do next?

Comment & Response

Associations Between the Global Cognitive Performance and the Optical Coherence Tomography Optic-Nerve Measurements

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1797

Associations Between the Global Cognitive Performance and the Optical Coherence Tomography Optic-Nerve Measurements

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1800

Associations Between the Global Cognitive Performance and the Optical Coherence Tomography Optic-Nerve Measurements—Reply

Abstract Full Text
JAMA Ophthalmol. Published online June 9, 2022. doi:10.1001/jamaophthalmol.2022.1803
June 2, 2022
Original Investigation

Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

Abstract Full Text
JAMA Ophthalmol. Published online June 2, 2022. doi:10.1001/jamaophthalmol.2022.1640

This epidemiologic follow-up study investigates the long-term findings of the Age-Related Macular Degeneration Study 2 (AREDS2) trial regarding lung cancer development and progression to age-related macular degeneration.

Association Between Retinal Microanatomy in Preterm Infants and 9-Month Visual Acuity

Abstract Full Text
JAMA Ophthalmol. Published online June 2, 2022. doi:10.1001/jamaophthalmol.2022.1643

This cohort study examines the association between preterm infant retinal microanatomy and visual acuity at 9 months’ corrected age.

JAMA Ophthalmology Clinical Challenge

Progressive Vision Loss in a Child With Cognitive Impairments

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online June 2, 2022. doi:10.1001/jamaophthalmol.2022.1015

A 9-year-old girl with a history of neonatal seizures presents to a pediatric retina service with progressive vision loss. What would you do next?

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